Autophagy and Longevity: A Precision Protocol for AMPK-mTOR Pathway Activation Through Daily Practices
Featured Paper 2026-07-29

Autophagy and Longevity: A Precision Protocol for AMPK-mTOR Pathway Activation Through Daily Practices

细胞自噬与延缓衰老的日常实践:基于AMPK-mTOR通路的精准激活方案

This paper reviews the molecular mechanisms of autophagy and presents a daily protocol combining intermittent fasting, exercise, and natural compounds to activate AMPK-mTOR pathways for longevity.

Research Archive 4 papers published

The Circadian Oscillator: A Molecular Triad of Light, Metabolism, and Mitochondria in Sleep Repair – Mechanistic Insights and Clinical Translational Strategies
Grade-A Evidence 2026-07-29

The Circadian Oscillator: A Molecular Triad of Light, Metabolism, and Mitochondria in Sleep Repair – Mechanistic Insights and Clinical Translational Strategies

This paper synthesizes recent findings from Harvard Medical School and Scripps Research, demonstrating how core clock genes govern sleep depth via mitochondrial dynamics and NAD+ metabolism, with three RCT-validated interventions.

The Hidden Inflammatory Switch: How Your Daily Omega-6 Intake Fuels Aging – A Lipid-Based Anti-Inflammatory Diet Protocol
Grade-A Evidence 2026-07-29

The Hidden Inflammatory Switch: How Your Daily Omega-6 Intake Fuels Aging – A Lipid-Based Anti-Inflammatory Diet Protocol

Drawing from Harvard Health and Nature research, this article reveals how the Omega-6/Omega-3 imbalance acts as a lipid metabolic switch driving chronic inflammation, and provides a precise fatty-acid balancing protocol.

The Metabolic Gating of Sleep: How Chronobiology and NAD+ Precursors Synergistically Restore Deep Sleep Architecture
Grade-A Evidence 2026-07-29

The Metabolic Gating of Sleep: How Chronobiology and NAD+ Precursors Synergistically Restore Deep Sleep Architecture

A mechanistic review of how the circadian clock gates mitochondrial autophagy via NAD+/SIRT1, and a time-restricted intervention protocol to restore slow-wave sleep.