A Copper-Based Compound Clears Toxic Alzheimer’s Proteins and Restores Memory Function: Mechanistic Evidence from Metal Homeostasis Remodeling
铜基化合物清除阿尔茨海默病毒性蛋白并恢复记忆：一项基于金属稳态重塑的临床前研究
Exploring health mechanisms and lifestyle strategies.
V
VITA Repository Longevity Science
🔬 Peer-Reviewed Database
Research Archive 11 papers published
A Widely Used Brain Health Supplement Is Associated with Reduced Lifespan in Men: A Systematic Review of Clinical and Mechanistic Evidence
流行脑部补充剂与男性寿命缩短的关联：一项基于临床与流行病学证据的系统性风险分析
This review demonstrates that a popular over-the-counter brain supplement is significantly linked to increased all-cause mortality in men, driven by mechanisms involving mitochondrial stress and epigenetic dysregulation.
Alzheimer’s Breakthrough: Restoring Two Hours of Sleep Without Clearing Brain Plaques
阿尔茨海默病突破：科学家在不清除脑斑块的情况下恢复两小时睡眠
A new study demonstrates that targeting a specific neural circuit, rather than clearing amyloid plaques, restores two hours of deep sleep in Alzheimer’s models, offering a novel intervention pathway for cognitive decline.
Autophagy and Longevity: A Precision Protocol for AMPK-mTOR Pathway Activation Through Daily Practices
细胞自噬与延缓衰老的日常实践：基于AMPK-mTOR通路的精准激活方案
This paper reviews the molecular mechanisms of autophagy and presents a daily protocol combining intermittent fasting, exercise, and natural compounds to activate AMPK-mTOR pathways for longevity.
Circadian Resynchronization: The Molecular Logic of Light–Microbiome Crosstalk in Sleep Architecture Repair
昼夜节律重塑：光信号与肠道微生物协同调控睡眠修复的分子逻辑
Drawing on recent clinical data from Harvard and Stanford, this paper reveals how photoperiod and gut microbiota synergistically repair deep sleep via the melatonin–short-chain fatty acid axis, and provides actionable circadian reset protocols.
Mycelial Textiles as a Living Biomaterial: Self-Assembly of Fungal Hyphal Networks for Sustainable Fabrication and Dermal Microenvironment Modulation
菌丝体纺织的生物学逻辑：基于真菌丝状网络自组装的柔性生物材料构建及其在皮肤微环境调控中的潜力
Exploring health mechanisms and lifestyle strategies.
Targeted GABAergic Modulation Restores Two Hours of Deep Sleep in Alzheimer’s Model Without Amyloid Clearance
阿尔茨海默病突破：科学家在不清除脑斑块的情况下恢复两小时深度睡眠
A new study demonstrates that pharmacologically targeting a specific GABAergic circuit in the hippocampus restores two hours of NREM sleep in an Alzheimer’s mouse model, independently of amyloid plaque burden.
The Anabolic-Sleep Axis: A Newly Identified Neural Circuit Linking Deep Sleep to Muscle Protein Synthesis, Adipose Lipolysis, and Glymphatic Clearance
深度睡眠的“代谢开关”：科学家揭示同步增肌、燃脂与脑修复的神经回路
This paper reviews a recently identified brainstem-to-cortex circuit that, during slow-wave sleep, simultaneously triggers muscle protein synthesis, adipose tissue lipolysis, and glymphatic clearance of neurotoxic metabolites.
The Metabolic Cost of Pharmaceutical Corruption: A Systems-Level Analysis of Oxidative Stress and Mitochondrial Dysfunction Induced by Bribery in Hospital Pharmacy Administration
医药腐败的代谢代价：医院药学部受贿案对医疗系统氧化应激与线粒体功能的系统损伤分析
Exploring health mechanisms and lifestyle strategies.
The Metabolic Gating of Sleep: How Chronobiology and NAD+ Precursors Synergistically Restore Deep Sleep Architecture
昼夜节律的“代谢开关”：NMN与时间生物学如何协同修复深度睡眠
A mechanistic review of how the circadian clock gates mitochondrial autophagy via NAD+/SIRT1, and a time-restricted intervention protocol to restore slow-wave sleep.
The Overlooked Etiology of Ischemic Stroke: A Mechanistic Reappraisal of Carotid Plaque Microembolism and Endothelial Glycocalyx Degradation
被忽视的卒中元凶：颈动脉斑块微栓塞与血管内皮糖萼损伤的重新发现
Exploring health mechanisms and lifestyle strategies.